Alpha Galactosidase (α-galactosidase, EC 3.2.1.22), from Aspergillus niger, is a glycoside hydrolase, an exoglycosidase that catalyzes the water of α-galactosidate, which is decomposed by energy. Melibiose, also known as melibiase, can be used to improve and eliminate anti-nutritional ingredients in feed and soy foods. It can realize B→O blood group transformation, prepare universal blood type, and play an important role in enzyme replacement therapy of Fabry disease in the medical field. It can also act on complex polysaccharides containing α-galactosidic linkages, glycoproteins. And sheath sugar. Alpha Galactosidase also has a transgalactosylation effect in the case where the substrate concentration is highly enriched, and this feature can be used for the synthesis of a terpene polyester and the preparation of a cyclodextrin derivative. Alpha-galactosidase is a non-side-effect biological enzyme preparation for the development of functional foods, and has been certified as a safe substance by FDA, GRAS, WHO/FAP, and JACFA.