General: Apixab is a potent, orally active, reversible, direct, and highly selective factor Xa active site inhibitor with antithrombotic activity. It inhibits free and thrombus-bound factor Xa and inhibits prothrombin activity. Apixab is an anticoagulant used to prevent venous thromboembolism and atrial fibrillation stroke. It is a direct factor Xa inhibitor. Apixab can be used for antithrombotic therapy in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI) of atrial fibrillation.

Million pharm has more then 12 years maufacturing apixb api powder and apixbn intermediates of 3 routes. We supplied 80% China pharmcy factories.

Function：Apixabcan prevent thrombin generation and thrombosis, and play an anticoagulant role by inhibiting coagulation factor Xa.

Drug efficacy: Apixab is the third new oral anticoagulan. It has been approved in Europe to prevent venous thromboembolic events in patients undergoing elective hip or knee replacement surgery.