Kola nut is the seed of the cola nut plant. Cola nut is used widely in Nigeria and many West African countries as part of traditional hospitality, cultural, and social ceremonies. It is also used to make medicine.

Kola nut is used for short-term relief of fatigue, depression, chronic fatigue syndrome (CFS), melancholy, lack of normal muscle tone (atony), exhaustion, dysentery, a type of diarrhea called atonic diarrhea, weight loss, and migraine headaches.

In foods and beverages, Kola nut is used as a flavoring ingredient.