Lomustine is a nitrosourea alkylator that exhibits anticancer chemotherapeutic activity. Lomustine is clinically used to treat various forms of cancer.
Formula |
C9H16CIN3O2 |
Molecular weight |
233.70 |
EINECS |
235-859-2 |
CAS RN |
13010-47-4 |
CAS Name |
|
Synonyms: |
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; (chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea; (cloro-2-etil)-1-cicloesil-3-nitrosourea; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoure; 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-ure; belustine; cecenu; ceenu; chloroethylcyclohexylnitrosourea; cinu; cyclohexylchloroethylnitrosourea; icig1109; n-(2-chloroethyl)-n’-cyclohexyl-n-nitroso-ure; nci-c04740; nsc79037; nsc-79037; rb1509; 1-chloro-3-cyclohexyl-1-ethyl-3-nitrosourea |
Minimum assay |
≥98% |
Minimum stability |
|
Form |
yellow powder |
Solubility |
Soluble in ethanol (47 mg/ml at 25 °C), chloroform, water (<1 mg/ml at 25 °C), DMSO (47 mg/ml at 25 °C), and acetone. |
Application |
|
Usage |
a highly lipid soluble drug, treating brain tumors |
Melting point ca. |
88-90 ºC |
Boiling point ca. |
354.07 °C |
Density g/cm3 (20°C) |
1.31g/cm3 |
Refractive index |
1.57 |
Flash point |
133.2°C |
Stability |
Stable under recommended storage conditions |
Percent Composition |
C 46.25%, H 6.90%, Cl 15.17%, N 17.98%, O 13.69% |
Packaging |
required by customer |
Delivery Time |
overnight (USA/Canada); 3-5 days (worldwide) |
Storage |
Store at 4° C |
Transport information |
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Lomustine is a type of chemotherapy drug known as an alkylating agent. These drugs work by sticking to one of the cancer cell's DNA strands. This stops the cell from growing and dividing into 2 new cells.
This medication is used to treat various types of cancer. Lomustine belongs to a class of drugs known as alkylating agents. It works by slowing or stopping the growth of cancer cells.
