Hexane is an alkane of six carbon atoms, with the chemical formula C6H14.

The term may refer to any of the five structural isomers with that formula, or to a mixture of them. In IUPACnomenclature, however, hexane is the unbranched isomer (n-hexane); the other four structures are named as methylatedderivatives of pentane and butane. IUPAC also uses the term as the root of many compounds with a linear six-carbon backbone, such as 2-methylhexane (C7H16), which is also called "isoheptane".

Hexanes are significant constituents of gasoline. They are all colorless liquids at room temperature, odorless when pure, with boiling points between 50 and 70 °C. They are widely used as cheap, relatively safe, largely unreactive, and easily evaporated non-polar solvents.