Introduction
Serratiopeptidase, which is a high-yield strain of Serratia, is extracted by deep submerged fermentation. This product is widely used in the medical field and is used as an alternative medicine in many countries (such as Japan) and has a long Application history.
Pharmacological Action
(1) Anti-inflammatory, swelling effect: 1 Inflammatory model of rats with thermal burns, vascular hyperpermeability can be inhibited after oral administration; 2 Oral can inhibit inflammatory edema of rat skin induced by anti-rat serum, It can inhibit cross-dish gum, dextran and serotonin. Rat inflammatory edema caused by various inflammatory substances such as bradykinin; 3 has strong ability to decompose inflammatory peptide bradykinin in vitro; 4 has strong solvency for fibrin and fibrin.
(2) Promote the sputum, the dissolution and excretion of the concentrated solution: 1 for patients with chronic paranasal sinusitis, the dry matter weight in the nasal sputum is reduced, the viscosity is decreased; 2 for rabbits exposed to sulfur dioxide gas and suffering from subacute bronchitis. The viscosity of the mash is significantly reduced.
(3) The role of promoting the displacement of antibiotics to the lesion: for patients with chronic paranasal sinusitis, it can promote the migration of ampicillin to the maxillary sinus.
Physical and chemical properties
Temperature range ：10 ° C ~ 60 ° C, the optimum temperature is 40 ° C ~ 50 ° C.
Effective pH range ：6.0~10.0, the best PH7.0~9.0.
Product specifications
Solid dosage form ：A yellowish solid powder with an enzyme activity of 2,000,000 IU/g;
Enzyme activity definition ：One nerepeptidase unit (IU) is equivalent to the amount of enzyme required to produce 1 ug of tyrosine per minute under the specified conditions (pH 9.0, 37 ° C) (product standard: Japanese Pharmacopoeia).
Applications
Serratiopeptidase has the function of decomposing mucus and pus, which can make liquefied liquefaction, accelerate the elimination, and promote cell renewal. It can help the antibiotics to metastasize to the lesion and enhance the antibiotic antibacterial effect.
Packaging and storage
Store ：Store at 4~5°C in cold storage. Under this storage condition, the shelf life of this product is 2 years.
Package ：25L plastic.
| Product Name | Serratiopeptidase | ||
| Other Name | NA | Country of Origin | China |
| Strain | Serratia sp. | Manufacture Date | JUN 07, 2019 |
| Batch Number | SLT19052701 | Expiration Date | JUN 06, 2021 |
| Package | 25 kg/bucket | Quantity | 225 kg |
| PROTOCOL | SPECIFICATIONS | RESULTS | METHOD |
| PHYSICAL & CHEMICAL ANALYSIS | |||
| Description | Light grey powder | Complies | Visual |
| Odor & Taste | Characteristic odor and taste | Complies | Taste |
| Moisture | NMT 7% | 4.47% | Moisture Analyzer |
| IDENTIFICATION | |||
| Identifiable Activity | Positive for Serratiopeptidase Activity | Complies | In-house |
| ACTIVITY | |||
| Serratiopeptidase activity | NLT 2000 SPU/mg | 2,430 | JP XVI，95077-02-4 |
| MICROBIOLOGICAL | |||
| Total bacteria count Coliform bacteria (CFU/g) Molds and Yeasts E.Coli Salmonella Staphylococcus aureus Pseudomonas aeruginosa | NMT 3,000 CFU/g NMT 30 CFU/g NMT 100 CFU/g Absent Absent Absent Absent | ＜10 CFU/g ＜10 CFU/g ＜10 CFU/g Not Detected Not Detected Not Detected Not Detected | FDA BAM Online Ch.3 FDA BAM Online Ch.4 FDA BAM Online Ch. 2 FDA BAM Online Ch.4 FDA BAM Online Ch.5 FDA BAM Online Ch.12 AOAC |
| HEAVY METALS | |||
| Lead Mercury Cadmium Arsenic | NMT 3 ppm NMT 0.1 ppm NMT 1 ppm NMT 1 ppm | ＜3 ppm ＜0.1 ppm ＜1 ppm ＜1 ppm | USP <231> USP <231> USP <231> USP <231> |
| Storage: Store in cool and dry place protected from light, keep drum close when not in use. Conclusion: Conforms to FCC Standards. Shelf Life: Shelf life under prescribed storage conditions and air-tight packing will be 2 years. The product COMPLIES with the above said specifications Approved by RICKY H. ZHU | |||
Packaging and storage
Solid food packaging bag, 25 kg / barrel.
Store in dry, cool and well ventilated places away from the sun, heat.
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